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Harold M. Frost (1921 - June 19, 2004) is an American orthopedist and surgeon considered one of the most important researchers and theorists in the field of bone biology and bone medicine in his day. He published nearly 500 scientific and clinical peer-reviewed articles and 16 books. According to the Science Citation Index, he is one of the most widely cited researchers in skeletal research.


Video Harold Frost



Kehidupan

He received his medical degree from Geisel School of Medicine and Feinberg School of Medicine in 1945. He then undertook a surgical internship in Worcester, Massachusetts. During this time he was an Officer at the Naval Medical Corps from 1946-1948. He then resumed his surgery at Orthopedic Surgery at Buffalo General and Children's Hospital in New York State from 1948 to 1953. In 1955, he became Assistant Professor of Orthopedic Surgery at Yale School of Medicine.

Dr. Frost moved to Detroit to take up a position at Henry Ford Hospital. There he became founder and Director of the Orthopedic Research Laboratory. He remained director until 1973, after serving as department chairman from 1966 to 1972.

During his stay at Henry Ford Hospital, Dr. Frost made many breakthroughs, which changed the paradigm of bone biology.

Frost moved to Pueblo, Colorado in 1973 - attracted by mountains, climate, and lifestyle - brought his international reputation as a steady researcher, talented and productive orthopedist. While there he continued his active participation in the Sun Valley Workshops where he interacted with participants to develop cancellous bone histomorphomety (1977), generating and improving the mechanostat hypothesis (1987), and the growing Paradigm of Bone Physiology (1997).

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Academic donation

The main academic input Dr. Harold M. Frost includes:

  • Development of Bone Histomorphometry for description of cell-based bone formation and bone resorption process
  • The eleventh rip biopsy is used for the diagnosis of metabolic bone disease
  • Research on multi-cellular units as the key to bone metabolism
  • Experimental evidence that Estrogen reduces bone formation
  • histological evidence of micro-damage to human bone biopsy
  • base model of plate adaptation Growth to mechanical stress
  • Utah-Paradigm of Bone physiology (Mechanostat-Theorem), an increase in Wolff's law which states that Bone adapts to mechanical stress and hence there is a close relationship between muscle and bone

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Books

  • Bone remodeling dynamics , surgical monographs of Henry Ford Hospital, Thomas (Springfield, Ill.), 1963
  • Legal structure of bone , surgical monograph of Henry Ford Hospital, Thomas (Springfield, Ill.), 1964
  • Mathematical Elements of Lamellar Bone Remodeling , surgical monographs of Henry Ford Hospital, Thomas (Springfield, Ill.), 1964
  • Biodynamic bone , Henry Ford Hospital's international symposium, [14], Little, Brown (Boston) 1964
  • Bone dynamics in osteoporosis and osteomalacia , surgical monographs of Henry Ford Hospital, Thomas (Springfield, Ill.), 1966
  • Introduction to biomechanics , Monographic Surgery, Thomas (Springfield, Ill., 1967, 0398028249
  • Orthopedic surgery in elasticity (Orthopedic lecture Vol 1) , Thomas (Springfield, Ill., 1972)
  • The physiology of cartilage, fibrous, and boned (Orthopedic lectures Vol 2) , Thomas (Springfield, Ill.), 1972, ISBN 0-398-02562-2
  • Bone remodeling and its association with bone metabolic disease (Orthopedic lectures Vol 3) , Thomas (Springfield, Ill., 1973, ISBNÃ, 0-398-02588-6
  • Bone modeling and bone modeling errors (Orthopedic Teaching Vol 4) , Thomas (Springfield, Ill., 1973, ISBNÃ, 0-398-02667-X
  • Orthopedic Biomechanics (Orthopedic Lecture Vol 5) , Thomas (Springfield, Ill., 1973, ISBNÃ, 0-398-02824-9
  • Symposium on Osteoporosis Part 1: Physiotherapy, Pathophysiology, and Diagnosis , Saunders (Philadelphia), 1981
  • Symposium on Osteoporosis Part 2: Therapy and Prevention , Saunders (Philadelphia), 1981
  • Framework intermediary organization , CRC Press (Boca Raton, Fla), 1986, ISBNÃ, 0-8493-5948-1
  • Bones in clinical orthopedics - Chapter 14: Determinants of bone strength and mass: summary and clinical implications by Geoff Sumner-Smith, Georg Thieme Verlag, 2002, ISBN Ã, 0-86577-829-9 , [1]
  • The Utah Paradigm of Skeletal Physiology Vol. 1 , ISMNI
  • The Utah Paradigm of Skeletal Physiology Vol. 2 , ISMNI

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References




External links

  • Respect for Harold Frost in the Neuronal Musculoskeletal Interaction Journal , 4 (4), 2004, 348-356
  • Harold M. Frost, M.D., D.Sc. (hon) - one person's association in Journal of Musculoskeletal Neuronal Interactions , 6 (2), 2006
  • Harold M Frost William F. Neuman Awardee 2001 at Journal of Musculoskeletal Neuronal Interactions , 2 (2), 2001, 117-119
  • ASBMR Harold M. Frost Young Investigator Award
  • ISMNI - International Society of Musculoskeletal and Neuronal Interactions
  • Sun Valley Workshop - Sun Valley IBMS Annual Workshop

Source of the article : Wikipedia

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