The white indium cells scan , also called " indium leukocyte imaging ", " indium-111 scan ", or just " indium scan ", is a nuclear medicine procedure in which white blood cells (mostly neutrophils) are removed from the patient, marked with Indium-111 radioisotopes, and then intravenously injected into the patient. The tagged leukocytes then localize to a relatively new area of ​​infection. This study is helpful in distinguishing conditions such as osteomyelitis from decubitus ulcers for route assessment and duration of antibiotic therapy.
In infection imaging, gallium scan has a sensitivity advantage over the scanning of indium white blood cells in the imaging of osteomyelitis (bone infection) of the spine, lung infections and inflammation, and in detecting chronic infection. In part, this is because gallium binds to neutrophil membranes, even after the death of neutrophils, whereas indigenous labeled neutrophils require them to be in a relatively good functional order. However, imaging of indium leukocytes is better for localized acute (ie, new) infections, where live neutrophils are still rapid and actively localize the infection, for imaging for osteomyelitis that does not involve the spine, and to find abdominal and pelvic infections.
Both gallium scan and indium-111 white blood cell imaging can be used to image unknown origin fever (high temperature without explanation). However, leukocyte indium scanning will only localize about 25% of cases caused by acute infection, while gallium is more widely sensitive, localizing other febrile sources, such as chronic infections and tumors. Gallium may be a better choice for spleen studies because gallium usually does not accumulate in the spleen.
Video Indium-111 WBC scan
See also
- Radiology
- Nuclear medicine
- Gallium Scan
- Indium-111
Maps Indium-111 WBC scan
References
Source of the article : Wikipedia
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